Entry Detail


General Information

Database ID:exR0721160
RNA Name:SNRPN
RNA Type:mRNA
Chromosome:chr15
Starnd:+
Coordinate:
Start Site(bp):24823637End Site(bp):24978723
External Links:ENSG00000128739



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCC4
chr13
95019835
95301475
-
ABRACL
chr6
139028745
139043302
+
AC006064.6
chr12
6556886
6607367
-
AC012254.2
chr18
47108188
47176345
-
AC068946.2
chr2
219209772
219222738
-
AC124312.1
chr15
24955034
25000276
+
AC137834.1
chr12
57249609
57296484
-
ACTB
chr7
5527148
5563784
-
ACTN4
chr19
38647649
38731589
+
ACTR1A
chr10
102461881
102502712
-
ACTR1B
chr2
97655939
97664044
-
ACVR1B
chr12
51951699
51997078
+
ACVR2B
chr3
38453890
38493142
+
AGO3
chr1
35930718
36072500
+
AKAP17A
chrX
1591604
1602520
+
AL136454.1
chr1
192716132
192716653
+
ALDH1B1
chr9
38392702
38398661
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC012467.2
chr3
53858994
53861576
-
AC067852.2
chr17
42552436
42554748
-
AC092490.1
chr12
8788253
8795789
+
AC106864.1
chr4
112693047
112706810
-
AL022311.1
chr22
37876148
37895563
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.