Entry Detail


General Information

Database ID:exR0721233
RNA Name:SOX4
RNA Type:mRNA
Chromosome:chr6
Starnd:+
Coordinate:
Start Site(bp):21593751End Site(bp):21598619
External Links:ENSG00000124766



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC011005.1
chr7
129126518
129130793
+
AC131160.1
chr3
183815568
183884889
-
AC135050.2
chr16
31083439
31094956
-
ACSF3
chr16
89088375
89164121
+
ACTR1A
chr10
102461881
102502712
-
ADGRL1
chr19
14147743
14206187
-
AEN
chr15
88621337
88632281
+
AFDN
chr6
167826922
167972023
+
AHCYL1
chr1
109984765
110023742
+
AKAP9
chr7
91940867
92110673
+
AKIRIN2
chr6
87674860
87702233
-
AL162417.1
chr9
133098121
133163914
-
ALDH16A1
chr19
49453225
49471050
+
ALDH1B1
chr9
38392702
38398661
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-25-3p
chr7
100093571
100093592
-
hsa-miR-92a-3p
chrX
134169544
134169565
-
hsa-miR-378a-3p
chr5
149732867
149732888
+
hsa-miR-422a
chr15
63870989
63871010
-
hsa-miR-92b-3p
chr1
155195237
155195258
+
hsa-miR-483-5p
chr11
2134181
2134202
-
hsa-miR-7704
chr2
176188843
176188861
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007637.1
chr12
109111218
109125594
+
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.