Entry Detail


General Information

Database ID:exR0721415
RNA Name:SRRM2
RNA Type:mRNA
Chromosome:chr16
Starnd:+
Coordinate:
Start Site(bp):2752626End Site(bp):2772538
External Links:ENSG00000167978



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCA2
chr9
137007234
137028922
-
ABCB8
chr7
151028422
151047782
+
ABCG2
chr4
88090150
88231628
-
ABI1
chr10
26746593
26861087
-
ABT1
chr6
26596953
26600739
+
AC010422.3
chr19
12643831
12648397
-
AC046185.1
chr17
63702845
63752097
-
AC092143.1
chr16
89919165
89936092
+
AC093525.1
chr16
2513965
2527955
+
AC104452.1
chr3
49416777
49429314
-
AC107871.1
chr15
68184032
68229718
-
AC120057.2
chr17
7240427
7244635
-
AC138811.2
chr16
18788063
18801519
-
ACTB
chr7
5527148
5563784
-
ACTN4
chr19
38647649
38731589
+
ADAM10
chr15
58588809
58749791
-
ADAM15
chr1
155050566
155062775
+
ADGRE5
chr19
14380501
14408725
+
ADGRL2
chr1
81306160
81992436
+
ADRM1
chr20
62302093
62308862
+
AGGF1
chr5
77029251
77065234
+
AGPAT1
chr6
32168212
32178096
-
AHNAK
chr11
62433542
62556235
-
AK4
chr1
65147549
65232145
+
AKT2
chr19
40230317
40285536
-
ALDH18A1
chr10
95605941
95656711
-
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-3648
chr21
8987026
8987046
+
hsa-miR-7847-3p
chr11
1880105
1880125
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005696.4
chr17
2720801
2723947
-
AC007952.4
chr17
19112000
19112636
-
AC016876.2
chr17
7581964
7584086
-
AC020663.1
chr16
4730115
4752565
-
AC026362.1
chr12
122975320
122982907
+
AC051619.7
chr15
45200325
45200632
-
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.