Entry Detail


General Information

Database ID:exR0721499
RNA Name:STAT3
RNA Type:mRNA
Chromosome:chr17
Starnd:-
Coordinate:
Start Site(bp):42313324End Site(bp):42388568
External Links:ENSG00000168610



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC114490.2
chr1
34981533
35031741
-
ACTG1
chr17
81509971
81523847
-
ADRA2A
chr10
111077029
111080907
+
AL133352.1
chr10
100505628
100529881
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-337-3p
chr14
100874553
100874574
+
hsa-miR-339-5p
chr7
1022990
1023012
-
hsa-miR-516b-5p
chr19
53736860
53736881
+
hsa-miR-671-5p
chr7
151238449
151238471
+
hsa-miR-423-5p
chr17
30117095
30117117
+
hsa-miR-1307-3p
chr10
103394301
103394322
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC009052.1
chr16
57461055
57462737
+
AC106864.1
chr4
112693047
112706810
-
AC245014.3
chr1
145281116
145281462
+
AD000090.1
chr19
35557956
35581954
+
AL121985.1
chr1
160670778
160699761
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.