Entry Detail


General Information

Database ID:exR0721629
RNA Name:SURF4
RNA Type:mRNA
Chromosome:chr9
Starnd:-
Coordinate:
Start Site(bp):133361450End Site(bp):133376166
External Links:ENSG00000148248



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCF1
chr6
30571393
30597179
+
ABL1
chr9
130713016
130887675
+
AC004832.3
chr22
30409255
30428990
+
AC087289.3
chr17
75898645
75930129
-
AC120057.2
chr17
7240427
7244635
-
ACTB
chr7
5527148
5563784
-
ACTL6A
chr3
179562886
179588407
+
ADRM1
chr20
62302093
62308862
+
AKAP17A
chrX
1591604
1602520
+
AKIRIN1
chr1
38991276
39006059
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-18a-5p
chr13
91350756
91350778
+
hsa-miR-3654
chr7
133034860
133034878
-
hsa-miR-4442
chr3
25664875
25664891
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC093249.6
chr16
30697707
30699058
-
AD000090.1
chr19
35557956
35581954
+
AL031282.2
chr1
1702736
1737688
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.