exRNAdisease

Entry Detail

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General Information

Database ID: exR0721644 RNA Name: SYAP1 RNA Type: mRNA Chromosome: chrX Starnd: + Coordinate: Start Site(bp): 16719612 End Site(bp): 16765340 External Links: ENSG00000169895

Disease Information

Disease Name: Lactation Disease Category: Other Diseases MeSH ID: D007774 Type: Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena Alias: Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations

Expression Detail

GEO ID: GSE36936 Description: Gene Expression in the Human Mammary Epithelium during Initiation of Lactation. Experimental Design: Time Series Case Disease Type: Lactation Case Disease SubType: NA Case Sample: Day 42 post delivery Control Sample: 6h post delivery Number of Case: 7 Number of Control: 7 Number of Samples: 14

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACER3 chr11 76860867 77026797 + ACSF3 chr16 89088375 89164121 + ACTB chr7 5527148 5563784 - ADCY1 chr7 45574140 45723116 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-302a-3p chr4 112648186 112648208 - hsa-miR-302b-3p chr4 112648489 112648511 - hsa-miR-302c-3p chr4 112648366 112648388 - hsa-miR-302d-3p chr4 112648006 112648028 - hsa-miR-373-3p chr19 53788748 53788770 + hsa-miR-520e-3p chr19 53675764 53675784 + hsa-miR-519c-3p chr19 53686522 53686543 + hsa-miR-520a-3p chr19 53690933 53690954 + hsa-miR-519b-3p chr19 53695263 53695284 + hsa-miR-520b-3p chr19 53701267 53701287 + hsa-miR-520c-3p chr19 53707506 53707527 + hsa-miR-520d-3p chr19 53720149 53720170 + hsa-miR-519a-3p chr19 53762397 53762418 + hsa-miR-488-3p chr1 177029374 177029394 - hsa-miR-302e chr11 7234771 7234787 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007952.4 chr17 19112000 19112636 - AC012186.2 chr16 46660696 46661591 - AC104971.3 chr18 58659858 58660524 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 22649065 Title: Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans Author: Mohammad MA, Hadsell DL, Haymond MW. Journal: Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76. Description: We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.