Entry Detail


General Information

Database ID:exR0721697
RNA Name:SYVN1
RNA Type:mRNA
Chromosome:chr11
Starnd:-
Coordinate:
Start Site(bp):65121780End Site(bp):65134533
External Links:ENSG00000162298



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ACIN1
chr14
23058564
23095614
-
ACSS1
chr20
25006230
25058980
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
AGBL5
chr2
27042364
27070622
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-148a-3p
chr7
25949922
25949943
-
hsa-miR-150-5p
chr19
49500832
49500853
-
hsa-miR-148b-3p
chr12
54337278
54337299
+
hsa-miR-324-3p
chr17
7223308
7223330
-
hsa-miR-483-3p
chr11
2134142
2134162
-
hsa-miR-512-3p
chr19
53666729
53666750
+
hsa-miR-642a-5p
chr19
45674943
45674964
+
hsa-miR-663a
chr20
26208243
26208264
-
hsa-miR-423-5p
chr17
30117095
30117117
+
hsa-miR-541-3p
chr14
101064548
101064569
+
hsa-miR-744-5p
chr17
12081909
12081930
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005899.4
chr17
32328441
32329395
+
AC139149.1
chr17
81514047
81527776
+
AD000090.1
chr19
35557956
35581954
+
AL136985.3
chr1
58715609
58771295
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.