Entry Detail


General Information

Database ID:exR0722029
RNA Name:THOC5
RNA Type:mRNA
Chromosome:chr22
Starnd:-
Coordinate:
Start Site(bp):29505879End Site(bp):29555216
External Links:ENSG00000100296



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABHD5
chr3
43690108
43734371
+
ABT1
chr6
26596953
26600739
+
AC048338.1
chr12
122207779
122266423
-
AC091959.3
chr5
146203550
146339251
+
AC245033.1
chr15
82536788
82573194
-
ACTN4
chr19
38647649
38731589
+
ACTR1B
chr2
97655939
97664044
-
ADCY5
chr3
123282296
123449758
-
ADH5
chr4
99070978
99088801
-
AFG3L2
chr18
12328944
12377227
-
AHCY
chr20
34280268
34311802
-
AKIP1
chr11
8911139
8920084
+
AL121758.1
chr20
646626
675800
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC006160.1
chr4
17586267
17614585
-
AC016026.1
chr22
17787652
17811497
-
AC091820.2
chr5
167287320
167294273
-
AC132217.1
chr11
2129121
2129964
-
AC245033.4
chr15
82533175
82540008
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.