Entry Detail


General Information

Database ID:exR0722092
RNA Name:TKT
RNA Type:mRNA
Chromosome:chr3
Starnd:-
Coordinate:
Start Site(bp):53224712End Site(bp):53256052
External Links:ENSG00000163931



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCF1
chr6
30571393
30597179
+
AC104532.1
chr19
5904841
5914707
+
AC245033.1
chr15
82536788
82573194
-
AC124312.1
chr15
24955034
25000276
+
AC008982.1
chr19
38817471
38840178
-
ACTR1A
chr10
102461881
102502712
-
ALDOA
chr16
30064164
30070457
+
ACO2
chr22
41469117
41528989
+
ACAP1
chr17
7336529
7351477
+
ABCA2
chr9
137007234
137028922
-
AC104109.3
chr5
134167170
134226071
-
ACLY
chr17
41866917
41930542
-
AC004922.1
chr7
99325879
99394653
+
AC068580.4
chr11
1734821
1763954
-
AL136454.1
chr1
192716132
192716653
+
AD000671.2
chr19
35739252
35745432
-
AGO4
chr1
35808016
35857890
+
AC138969.1
chr16
16317444
16350590
+
ACTB
chr7
5527148
5563784
-
AC007192.1
chr19
18153158
18178117
+
ADAR
chr1
154582057
154628013
-
ACTG1
chr17
81509971
81523847
-
AKT1
chr14
104769349
104795751
-
AC010615.4
chr19
21405159
21491266
+
AC018523.2
chr11
14493783
14520344
-
AC004832.3
chr22
30409255
30428990
+
ADSL
chr22
40346500
40390463
+
AKAP12
chr6
151239967
151358559
+
AL022238.4
chr22
40346529
40410054
+
ADRM1
chr20
62302093
62308862
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC012236.1
chr15
31221999
31230838
-
AC087521.3
chr11
43921059
44001157
+
AC091564.7
chr11
6610883
6616594
-
AC091729.3
chr7
1160374
1165607
+
AC245014.3
chr1
145281116
145281462
+
AD000090.1
chr19
35557956
35581954
+
AL031282.2
chr1
1702736
1737688
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.