Entry Detail


General Information

Database ID:exR0722364
RNA Name:TMSB4X
RNA Type:mRNA
Chromosome:chrX
Starnd:+
Coordinate:
Start Site(bp):12975110End Site(bp):12977227
External Links:ENSG00000205542



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ACTB
chr7
5527148
5563784
-
ACTR2
chr2
65227753
65271253
+
AC006064.6
chr12
6556886
6607367
-
ADH5
chr4
99070978
99088801
-
ADPRH
chr3
119579268
119589945
+
ADGRL1
chr19
14147743
14206187
-
AGO2
chr8
140520156
140635633
-
AKT1
chr14
104769349
104795751
-
AC012184.2
chr16
70299194
70372582
+
AC093525.1
chr16
2513965
2527955
+
ADRM1
chr20
62302093
62308862
+
ALDOA
chr16
30064164
30070457
+
AC023055.1
chr12
55757275
55827546
-
AC139530.2
chr17
81703371
81720539
+
AL162417.1
chr9
133098121
133163914
-
AC048338.1
chr12
122207779
122266423
-
AL021546.1
chr12
120438198
120460006
+
AC073508.2
chr17
40627356
40665141
-
ABT1
chr6
26596953
26600739
+
AC073896.1
chr12
56285916
56316059
-
ABHD5
chr3
43690108
43734371
+
AGPAT5
chr8
6708642
6761503
+
ADSL
chr22
40346500
40390463
+
ADORA2A
chr22
24417879
24442357
+
ACAP1
chr17
7336529
7351477
+
AKAP13
chr15
85380571
85749358
+
ACTR1A
chr10
102461881
102502712
-
AFTPH
chr2
64524305
64593005
+
ADD2
chr2
70607618
70768225
-
ACOT7
chr1
6264269
6394391
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-142-3p
chr17
58331245
58331267
-
hsa-miR-155-5p
chr21
25573983
25574006
+
hsa-miR-4442
chr3
25664875
25664891
-
hsa-miR-7847-3p
chr11
1880105
1880125
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004554.2
chrX
11668401
11757718
-
AC004687.1
chr17
58330884
58332508
-
AC005618.1
chr5
141326210
141329357
+
AC005899.4
chr17
32328441
32329395
+
AC007744.1
chr2
56147630
56386171
+
AC007780.1
chr17
68413623
68524949
+
AC007952.4
chr17
19112000
19112636
-
AC010247.1
chr19
42132555
42137099
+
AC017104.1
chr2
231388976
231394991
+
AC022167.2
chr16
8848105
8860456
+
AC024940.6
chr12
31280422
31280895
-
AC026362.1
chr12
122975320
122982907
+
AC026461.1
chr16
56682470
56687807
+
AC026471.1
chr16
31456711
31459736
-
AC055854.1
chr8
22690150
22798616
+
AC063949.2
chr12
92421531
92483680
+
AC073896.4
chr12
56162359
56190284
-
AC114271.1
chr19
10333436
10336248
+
AC139149.1
chr17
81514047
81527776
+
AC245014.3
chr1
145281116
145281462
+
AD000090.1
chr19
35557956
35581954
+
AJ271736.1
chrX
156004218
156022236
+
AL022311.1
chr22
37876148
37895563
+
AL035458.2
chr20
34234840
34281173
-
AL096870.2
chr14
24209646
24215987
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.