Entry Detail


General Information

Database ID:exR0722418
RNA Name:TNIP1
RNA Type:mRNA
Chromosome:chr5
Starnd:-
Coordinate:
Start Site(bp):151029945End Site(bp):151093577
External Links:ENSG00000145901



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004922.1
chr7
99325879
99394653
+
AC007192.1
chr19
18153158
18178117
+
ACLY
chr17
41866917
41930542
-
ACTA1
chr1
229431245
229434098
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ADA
chr20
44619522
44652233
-
ADPRHL2
chr1
36088892
36093932
+
AHSA1
chr14
77457870
77469472
+
AK4
chr1
65147549
65232145
+
AL121753.1
chr20
35267885
35280043
-
AL133352.1
chr10
100505628
100529881
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004687.1
chr17
58330884
58332508
-
AC007744.1
chr2
56147630
56386171
+
AC016876.2
chr17
7581964
7584086
-
AC092159.2
chr2
692083
693235
-
AD000090.1
chr19
35557956
35581954
+
AL078612.2
chr11
32097143
32105091
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.