Entry Detail


General Information

Database ID:exR0722434
RNA Name:TNPO2
RNA Type:mRNA
Chromosome:chr19
Starnd:-
Coordinate:
Start Site(bp):12699194End Site(bp):12724011
External Links:ENSG00000105576



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AAMP
chr2
218264123
218270257
-
ABCE1
chr4
145098288
145129524
+
ABL2
chr1
179099330
179229684
-
AC007040.2
chr2
70939318
70995336
-
AC010422.3
chr19
12643831
12648397
-
AC011462.1
chr19
41350853
41425001
+
AC011530.1
chr19
45779437
45785973
-
AC091167.2
chr15
90249556
90272208
+
AC092647.5
chr7
55887277
55955239
+
ACACA
chr17
37084992
37406836
-
ACADVL
chr17
7217125
7225266
+
ACTB
chr7
5527148
5563784
-
ADAM11
chr17
44758988
44781846
+
ADAM8
chr10
133262420
133276868
-
ADARB1
chr21
45073853
45226560
+
ADCK2
chr7
140672945
140696261
+
ADGRE5
chr19
14380501
14408725
+
ADGRG2
chrX
18989307
19122637
-
AGAP1
chr2
235494043
236131800
+
AGAP3
chr7
151085831
151144436
+
AGPAT5
chr8
6708642
6761503
+
AGRN
chr1
1020120
1056118
+
AL136295.4
chr14
24180395
24190416
-
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-4787-5p
chr3
50675093
50675114
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC006538.1
chr19
2727743
2729327
-
AC011753.2
chr2
109594693
109605698
-
AC084125.2
chr8
144495458
144505444
-
AC109460.3
chr16
28974804
28990775
+
AD000090.1
chr19
35557956
35581954
+
AGAP11
chr10
86970741
87010126
+
AL049796.1
chr1
93847174
93848939
+
AL117379.1
chr20
62928621
62929297
-
AL136982.1
chr10
86992406
87010203
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.