Entry Detail


General Information

Database ID:exR0722520
RNA Name:TPT1
RNA Type:mRNA
Chromosome:chr13
Starnd:-
Coordinate:
Start Site(bp):45333471End Site(bp):45341370
External Links:ENSG00000133112



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCB4
chr7
87401697
87480435
-
AK2
chr1
33007940
33080996
-
AKAP17A
chrX
1591604
1602520
+
AARSD1
chr17
42950526
42964498
-
AGBL2
chr11
47659591
47715389
-
AC092718.8
chr16
81022316
81096284
-
AKAP1
chr17
57085092
57121346
+
ADM
chr11
10305073
10307397
+
AL136454.1
chr1
192716132
192716653
+
AAGAB
chr15
67200667
67255195
-
ACAP1
chr17
7336529
7351477
+
AC105052.1
chr7
102582523
102642869
-
AC112229.3
chr2
110402934
110473075
-
AL121594.1
chr14
35122549
35317474
+
ABR
chr17
1003518
1229738
-
AC005258.1
chr19
2269525
2341172
+
AIFM2
chr10
70098223
70132934
-
ADK
chr10
74151202
74709963
+
AL121753.1
chr20
35267885
35280043
-
ACIN1
chr14
23058564
23095614
-
AC073082.1
chr2
48632291
48755724
-
AGO4
chr1
35808016
35857890
+
AC073508.2
chr17
40627356
40665141
-
AC120057.2
chr17
7240427
7244635
-
AC010323.1
chr19
8308283
8321379
-
ACBD3
chr1
226144679
226186741
-
ADAR
chr1
154582057
154628013
-
ACTR1B
chr2
97655939
97664044
-
ACAD8
chr11
134253495
134265855
+
ADD3
chr10
109996368
110135565
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-3648
chr21
8987026
8987046
+
hsa-miR-4426
chr1
192716333
192716349
+
hsa-miR-4700-5p
chr12
120723202
120723223
+
hsa-miR-4700-3p
chr12
120723233
120723258
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005062.1
chr7
19918981
20140453
-
AC007952.4
chr17
19112000
19112636
-
AC012321.1
chr16
69703065
69704652
+
AC012531.2
chr12
54017110
54035361
+
AC016876.2
chr17
7581964
7584086
-
AC019155.2
chr7
125229579
125264291
-
AC020663.1
chr16
4730115
4752565
-
AC026362.1
chr12
122975320
122982907
+
AC064802.1
chr8
114282067
114295839
+
AC079781.5
chr7
97851688
97972985
-
AC091564.7
chr11
6610883
6616594
-
AC113414.1
chr5
162424042
163437326
-
AC132217.1
chr11
2129121
2129964
-
AC242426.2
chr1
147172755
147295734
+
AD000090.1
chr19
35557956
35581954
+
AL022311.1
chr22
37876148
37895563
+
AL096870.2
chr14
24209646
24215987
-
AL121749.1
chr10
35604485
35608153
-
AL136295.6
chr14
24198433
24199090
+
AL137058.2
chr13
52600042
52642542
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.