Entry Detail


General Information

Database ID:exR0722585
RNA Name:TRIM28
RNA Type:mRNA
Chromosome:chr19
Starnd:+
Coordinate:
Start Site(bp):58544064End Site(bp):58550722
External Links:ENSG00000130726



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABHD14A-ACY1
chr3
51974706
51989183
+
AC005258.1
chr19
2269525
2341172
+
AC007192.1
chr19
18153158
18178117
+
AC008982.1
chr19
38817471
38840178
-
AC010422.3
chr19
12643831
12648397
-
AC092647.5
chr7
55887277
55955239
+
AC118553.2
chr1
99970011
100083321
+
AC129492.3
chr17
8150816
8162975
-
AC138811.2
chr16
18788063
18801519
-
AC245033.1
chr15
82536788
82573194
-
ACBD6
chr1
180269653
180502954
-
ACLY
chr17
41866917
41930542
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ACTR1A
chr10
102461881
102502712
-
ACTR3C
chr7
150243916
150323725
-
ACY1
chr3
51983340
51989197
+
ADAM10
chr15
58588809
58749791
-
ADAR
chr1
154582057
154628013
-
ADD1
chr4
2843857
2930076
+
ADSL
chr22
40346500
40390463
+
AHCY
chr20
34280268
34311802
-
AHDC1
chr1
27534035
27604431
-
AIDA
chr1
222668013
222713210
-
AK2
chr1
33007940
33080996
-
AKAP12
chr6
151239967
151358559
+
AKR1A1
chr1
45550543
45570049
+
AL121758.1
chr20
646626
675800
-
AL136295.5
chr14
24147548
24166452
+
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-6807-5p
chr19
58550285
58550306
+
hsa-miR-6807-3p
chr19
58550354
58550376
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC060780.1
chr17
43148368
43171037
-
AC069281.2
chr7
100572232
100578700
-
AC109460.3
chr16
28974804
28990775
+
AD000090.1
chr19
35557956
35581954
+
AL022311.1
chr22
37876148
37895563
+
AL117378.1
chr6
131901963
131920565
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.