Entry Detail


General Information

Database ID:exR0722805
RNA Name:TUBA1B
RNA Type:mRNA
Chromosome:chr12
Starnd:-
Coordinate:
Start Site(bp):49127782End Site(bp):49131397
External Links:ENSG00000123416



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ADIPOR1
chr1
202940826
202958572
-
AKIRIN1
chr1
38991276
39006059
+
AEN
chr15
88621337
88632281
+
ADCY5
chr3
123282296
123449758
-
ALDOA
chr16
30064164
30070457
+
AK2
chr1
33007940
33080996
-
ADRM1
chr20
62302093
62308862
+
ABRACL
chr6
139028745
139043302
+
ACSS2
chr20
34872146
34927962
+
AGFG2
chr7
100539203
100568220
+
ACTN4
chr19
38647649
38731589
+
AGBL5
chr2
27042364
27070622
+
ABI2
chr2
203328239
203447728
+
AC008878.3
chr19
7382834
7470241
+
ADGRG6
chr6
142301854
142446266
+
ACVR2B
chr3
38453890
38493142
+
AC120057.2
chr17
7240427
7244635
-
AC138811.2
chr16
18788063
18801519
-
ABHD14A-ACY1
chr3
51974706
51989183
+
ADD1
chr4
2843857
2930076
+
AC004922.1
chr7
99325879
99394653
+
ADSL
chr22
40346500
40390463
+
ACTG1
chr17
81509971
81523847
-
ADA
chr20
44619522
44652233
-
AC007192.1
chr19
18153158
18178117
+
AC007040.2
chr2
70939318
70995336
-
AC015813.2
chr17
57989038
58007246
-
ADAR
chr1
154582057
154628013
-
AC011448.1
chr19
19516227
19536076
+
AL136454.1
chr1
192716132
192716653
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-103a-3p
chr5
168560904
168560926
-
hsa-miR-106a-5p
chrX
134170244
134170266
-
hsa-miR-221-3p
chrX
45746180
45746202
-
hsa-miR-302c-3p
chr4
112648366
112648388
-
hsa-miR-652-3p
chrX
110055389
110055409
+
hsa-miR-1291
chr12
48654494
48654517
-
hsa-miR-3654
chr7
133034860
133034878
-
hsa-miR-4707-5p
chr14
22956998
22957020
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005618.1
chr5
141326210
141329357
+
AC007952.4
chr17
19112000
19112636
-
AC012485.1
chr2
238231684
238255633
+
AC016876.2
chr17
7581964
7584086
-
AC022167.2
chr16
8848105
8860456
+
AC023509.1
chr12
53441741
53467528
+
AC026362.1
chr12
122975320
122982907
+
AC069281.2
chr7
100572232
100578700
-
AC087190.3
chr16
9104848
9113181
+
AC104461.1
chr1
200333193
200478669
+
AC124067.3
chr8
37559992
37567477
+
AC245014.3
chr1
145281116
145281462
+
AD000090.1
chr19
35557956
35581954
+
AL049543.1
chr6
28587378
28591747
+
AL118516.1
chr22
46761894
46762563
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.