Entry Detail


General Information

Database ID:exR0722812
RNA Name:TUBB
RNA Type:mRNA
Chromosome:chr6
Starnd:+
Coordinate:
Start Site(bp):30720352End Site(bp):30725426
External Links:ENSG00000196230



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AIF1L
chr9
131096476
131123152
+
AHI1
chr6
135283532
135497765
-
AC091959.3
chr5
146203550
146339251
+
ADGRL2
chr1
81306160
81992436
+
AL022238.4
chr22
40346529
40410054
+
ACADS
chr12
120725774
120740008
+
AC015813.2
chr17
57989038
58007246
-
AATF
chr17
36948954
37056871
+
AACS
chr12
125065434
125143333
+
AKR1A1
chr1
45550543
45570049
+
AC025165.3
chr12
57772660
57797554
+
ADGRV1
chr5
90529344
91164437
+
AGO1
chr1
35869808
35930532
+
ABHD10
chr3
111979010
111993368
+
AC010132.3
chr7
42909273
42932174
-
ACAP1
chr17
7336529
7351477
+
AC048338.1
chr12
122207779
122266423
-
AC006030.1
chr2
74211604
74363377
-
ADH5
chr4
99070978
99088801
-
ACBD6
chr1
180269653
180502954
-
AAMP
chr2
218264123
218270257
-
AIG1
chr6
143060496
143341058
+
ACTB
chr7
5527148
5563784
-
AC013394.1
chr15
92883413
92949230
+
AL590132.1
chr1
210858125
211134146
-
AHSA1
chr14
77457870
77469472
+
ALDH18A1
chr10
95605941
95656711
-
AKAP8
chr19
15353385
15379798
-
ACTG1
chr17
81509971
81523847
-
ACTR3
chr2
113890063
113962596
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-92a-3p
chrX
134169544
134169565
-
hsa-miR-3198
chr12
54231407
54231428
-
hsa-miR-3654
chr7
133034860
133034878
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC002470.2
chr22
20979462
20998121
+
AC004687.1
chr17
58330884
58332508
-
AC010729.1
chr2
5726253
5730355
+
AC012360.3
chr2
105334027
105337475
-
AC016876.2
chr17
7581964
7584086
-
AC019205.1
chr6
73263212
73301789
+
AC022167.2
chr16
8848105
8860456
+
AC023509.1
chr12
53441741
53467528
+
AC026362.1
chr12
122975320
122982907
+
AC068134.1
chr2
232379635
232381674
-
AC092171.3
chr7
5426277
5428927
-
AC099522.2
chr5
73497550
73498293
-
AC114271.1
chr19
10333436
10336248
+
AC245014.3
chr1
145281116
145281462
+
AD000090.1
chr19
35557956
35581954
+
AL022311.1
chr22
37876148
37895563
+
AL023653.1
chrX
129794994
129796963
+
AL049543.1
chr6
28587378
28591747
+
AL132780.1
chr14
22929607
22956374
+
AL133215.2
chr10
101060029
101061005
-
AL137058.2
chr13
52600042
52642542
+
AL137127.1
chr1
19072110
19075511
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.