Entry Detail


General Information

Database ID:exR0722827
RNA Name:TUFM
RNA Type:mRNA
Chromosome:chr16
Starnd:-
Coordinate:
Start Site(bp):28842411End Site(bp):28846348
External Links:ENSG00000178952



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005832.4
chr12
4604944
4662643
+
AC011511.4
chr19
10315471
10320678
-
AC079594.2
chr3
160227454
160449829
-
AC092073.1
chr19
34396315
34409364
+
AC120057.2
chr17
7240427
7244635
-
ACP1
chr2
264140
278283
+
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ADD1
chr4
2843857
2930076
+
AHCY
chr20
34280268
34311802
-
AKT1
chr14
104769349
104795751
-
AKTIP
chr16
53491040
53504411
-
AL121845.3
chr20
63708864
63739103
+
AL590764.2
chrX
71103987
71111575
-
AL669918.1
chr6
32813767
32838822
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-3654
chr7
133034860
133034878
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC013268.5
chr2
109937438
109985124
+
AC023509.1
chr12
53441741
53467528
+
AC139149.1
chr17
81514047
81527776
+
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.