Entry Detail


General Information

Database ID:exR0722854
RNA Name:TXNIP
RNA Type:mRNA
Chromosome:chr1
Starnd:-
Coordinate:
Start Site(bp):145992435End Site(bp):145996579
External Links:ENSG00000265972



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AASDHPPT
chr11
106075501
106098699
+
AC135050.2
chr16
31083439
31094956
-
ACTA1
chr1
229431245
229434098
-
ACTG1
chr17
81509971
81523847
-
ADAR
chr1
154582057
154628013
-
ADCK2
chr7
140672945
140696261
+
AGO3
chr1
35930718
36072500
+
AHCY
chr20
34280268
34311802
-
AL121753.1
chr20
35267885
35280043
-
AL136295.5
chr14
24147548
24166452
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-302a-3p
chr4
112648186
112648208
-
hsa-miR-302b-3p
chr4
112648489
112648511
-
hsa-miR-302c-3p
chr4
112648366
112648388
-
hsa-miR-302d-3p
chr4
112648006
112648028
-
hsa-miR-302e
chr11
7234771
7234787
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007952.4
chr17
19112000
19112636
-
AC010655.4
chr7
128455840
128493859
+
AC245014.3
chr1
145281116
145281462
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.