Entry Detail


General Information

Database ID:exR0722890
RNA Name:UBB
RNA Type:mRNA
Chromosome:chr17
Starnd:+
Coordinate:
Start Site(bp):16380798End Site(bp):16382745
External Links:ENSG00000170315



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCF2
chr7
151207837
151227166
-
ABRACL
chr6
139028745
139043302
+
AC005258.1
chr19
2269525
2341172
+
AC006064.6
chr12
6556886
6607367
-
AC008763.3
chr19
7678501
7682854
+
AC010422.3
chr19
12643831
12648397
-
AC026954.2
chr17
7312661
7319174
-
AC027644.4
chr7
66628958
66811189
+
AC104452.1
chr3
49416777
49429314
-
ACIN1
chr14
23058564
23095614
-
ACLY
chr17
41866917
41930542
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ADARB1
chr21
45073853
45226560
+
ADCY6
chr12
48766194
48789037
-
AGBL5
chr2
27042364
27070622
+
AGPAT4
chr6
161129967
161274061
-
AK2
chr1
33007940
33080996
-
AKR1A1
chr1
45550543
45570049
+
AKR7A2
chr1
19303965
19312146
-
AL136454.1
chr1
192716132
192716653
+
AL136531.2
chr20
1317571
1393096
-
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-4426
chr1
192716333
192716349
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC006064.5
chr12
6510275
6510522
+
AC008014.1
chr12
46383652
46876784
+
AC069281.2
chr7
100572232
100578700
-
AC073062.1
chr2
13537673
13609168
+
AC107959.2
chr8
23068229
23083619
+
AC126365.1
chr17
20788071
20789584
+
AD000090.1
chr19
35557956
35581954
+
AL117378.1
chr6
131901963
131920565
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.