Entry Detail


General Information

Database ID:exR0722897
RNA Name:UBE2D3
RNA Type:mRNA
Chromosome:chr4
Starnd:-
Coordinate:
Start Site(bp):102794383End Site(bp):102868896
External Links:ENSG00000109332



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AATF
chr17
36948954
37056871
+
ABCB7
chrX
75051048
75156732
-
AC010422.3
chr19
12643831
12648397
-
AC017083.3
chr2
68131238
68261230
-
AC022384.1
chr3
10249372
10285796
+
AC084337.2
chr11
6481485
6508978
+
AC092143.1
chr16
89919165
89936092
+
ACACA
chr17
37084992
37406836
-
ACSL3
chr2
222860942
222944639
+
ACTB
chr7
5527148
5563784
-
ACTR3
chr2
113890063
113962596
+
ACTR6
chr12
100199122
100241865
+
ACYP1
chr14
75053237
75069483
-
ADD3
chr10
109996368
110135565
+
ADGRV1
chr5
90529344
91164437
+
AGL
chr1
99850361
99924023
+
AHCYL1
chr1
109984765
110023742
+
AHSA1
chr14
77457870
77469472
+
AIF1L
chr9
131096476
131123152
+
AK4
chr1
65147549
65232145
+
AKIRIN2
chr6
87674860
87702233
-
AKR1A1
chr1
45550543
45570049
+
ALDOA
chr16
30064164
30070457
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC009133.5
chr16
29808679
29812227
+
AC020663.1
chr16
4730115
4752565
-
AL117378.1
chr6
131901963
131920565
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.