Entry Detail


General Information

Database ID:exR0722924
RNA Name:UBE2Z
RNA Type:mRNA
Chromosome:chr17
Starnd:+
Coordinate:
Start Site(bp):48908407End Site(bp):48929056
External Links:ENSG00000159202



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABI2
chr2
203328239
203447728
+
AC008982.1
chr19
38817471
38840178
-
AC010422.3
chr19
12643831
12648397
-
ACAD10
chr12
111686056
111757107
+
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ACTR1A
chr10
102461881
102502712
-
ADAR
chr1
154582057
154628013
-
ADGRL1
chr19
14147743
14206187
-
AEBP2
chr12
19404045
19720801
+
AGAP3
chr7
151085831
151144436
+
AGPAT3
chr21
43865223
43987592
+
AHCY
chr20
34280268
34311802
-
AICDA
chr12
8602170
8612867
-
AKIRIN2
chr6
87674860
87702233
-
AL121594.1
chr14
35122549
35317474
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-18a-5p
chr13
91350756
91350778
+
hsa-miR-18b-5p
chrX
134170084
134170106
-
hsa-miR-625-5p
chr14
65471116
65471136
+
hsa-miR-654-5p
chr14
101040234
101040255
+
hsa-miR-423-5p
chr17
30117095
30117117
+
hsa-miR-708-5p
chr11
79402077
79402099
-
hsa-miR-1224-5p
chr3
184241405
184241423
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC016876.2
chr17
7581964
7584086
-
AC105036.3
chr15
75527150
75601205
-
AC125807.2
chr12
3041437
3044950
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.