Entry Detail


General Information

Database ID:exR0722950
RNA Name:UBR4
RNA Type:mRNA
Chromosome:chr1
Starnd:-
Coordinate:
Start Site(bp):19074510End Site(bp):19210266
External Links:ENSG00000127481



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCF1
chr6
30571393
30597179
+
ABHD13
chr13
108218392
108234243
+
ABI2
chr2
203328239
203447728
+
ABL2
chr1
179099330
179229684
-
AC093525.2
chr16
2496032
2520218
+
AC138894.1
chr16
28456371
28492098
-
ACD
chr16
67657512
67660815
-
ACIN1
chr14
23058564
23095614
-
ACTB
chr7
5527148
5563784
-
ADORA2A
chr22
24417879
24442357
+
AFG3L2
chr18
12328944
12377227
-
AGAP3
chr7
151085831
151144436
+
AGO2
chr8
140520156
140635633
-
AHCY
chr20
34280268
34311802
-
AK7
chr14
96392128
96489427
+
AKAP13
chr15
85380571
85749358
+
AL138752.2
chr9
37588413
38068687
-
AL139300.1
chr14
103562962
103685924
+
AL357673.1
chr1
54132686
54200073
-
AL513165.2
chr9
37512547
37592469
-
ALCAM
chr3
105366909
105576900
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-3620-3p
chr1
228097320
228097341
+
hsa-miR-5100
chr10
42997630
42997651
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
A1BG-AS1
chr19
58347718
58355455
+
AC109460.3
chr16
28974804
28990775
+
AD000090.1
chr19
35557956
35581954
+
AL096870.2
chr14
24209646
24215987
-
AL137127.1
chr1
19072110
19075511
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.