Entry Detail


General Information

Database ID:exR0723083
RNA Name:USP22
RNA Type:mRNA
Chromosome:chr17
Starnd:-
Coordinate:
Start Site(bp):20999596End Site(bp):21043760
External Links:ENSG00000124422



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AARS2
chr6
44298731
44313347
-
ABCB1
chr7
87503017
87713323
-
AC005726.1
chr17
28455752
28614185
-
AC008581.2
chr5
77030902
77152155
+
AC008695.1
chr5
131425891
131796983
-
AC010422.3
chr19
12643831
12648397
-
AC138811.2
chr16
18788063
18801519
-
ACBD3
chr1
226144679
226186741
-
ACIN1
chr14
23058564
23095614
-
ACLY
chr17
41866917
41930542
-
ADH5
chr4
99070978
99088801
-
ADSL
chr22
40346500
40390463
+
AGGF1
chr5
77029251
77065234
+
AHCY
chr20
34280268
34311802
-
AKR1B1
chr7
134442356
134459284
-
AL022238.4
chr22
40346529
40410054
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-148b-3p
chr12
54337278
54337299
+
hsa-miR-485-5p
chr14
101055427
101055448
+
hsa-miR-650
chr22
22822791
22822811
+
hsa-miR-371a-5p
chr19
53787680
53787699
+
hsa-miR-616-3p
chr12
57519183
57519204
-
hsa-miR-665
chr14
100875075
100875094
+
hsa-miR-1321
chrX
85835832
85835849
+
hsa-miR-4508
chr15
23562107
23562123
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC006064.5
chr12
6510275
6510522
+
AC007952.4
chr17
19112000
19112636
-
AC011445.1
chr19
39314651
39320858
-
AC016876.2
chr17
7581964
7584086
-
AC026362.1
chr12
122975320
122982907
+
AC067852.1
chr17
42536510
42562062
+
AC067930.1
chr8
143579636
143580670
+
AC087190.3
chr16
9104848
9113181
+
AC111170.2
chr17
77469162
77472770
-
AC133644.3
chr2
87455476
87767359
+
AD000090.1
chr19
35557956
35581954
+
AL022311.1
chr22
37876148
37895563
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.