Entry Detail


General Information

Database ID:exR0723152
RNA Name:VAT1
RNA Type:mRNA
Chromosome:chr17
Starnd:-
Coordinate:
Start Site(bp):43014607End Site(bp):43025123
External Links:ENSG00000108828



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCC10
chr6
43427366
43450427
+
ABHD17B
chr9
71862452
71910931
-
AC006486.1
chr19
42234583
42255132
-
AC010422.3
chr19
12643831
12648397
-
AC093525.2
chr16
2496032
2520218
+
AC245033.1
chr15
82536788
82573194
-
ACTB
chr7
5527148
5563784
-
ACTC1
chr15
34790230
34795549
-
ACTG1
chr17
81509971
81523847
-
ACTN1
chr14
68874143
68979440
-
ACTN3
chr11
66546395
66563334
+
ADAM15
chr1
155050566
155062775
+
ADPGK
chr15
72751369
72785846
-
AIF1L
chr9
131096476
131123152
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-23a-3p
chr19
13836595
13836615
-
hsa-miR-124-3p
chr8
64379210
64379231
+
hsa-miR-642a-5p
chr19
45674943
45674964
+
hsa-miR-769-5p
chr19
46018961
46018982
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC008753.2
chr19
53788782
53789168
+
AC020663.1
chr16
4730115
4752565
-
AC026362.1
chr12
122975320
122982907
+
AC245014.3
chr1
145281116
145281462
+
AC245033.4
chr15
82533175
82540008
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.