Entry Detail


General Information

Database ID:exR0723162
RNA Name:VCL
RNA Type:mRNA
Chromosome:chr10
Starnd:+
Coordinate:
Start Site(bp):73995193End Site(bp):74121363
External Links:ENSG00000035403



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCB6
chr2
219209772
219218994
-
ABCF1
chr6
30571393
30597179
+
ABHD14B
chr3
51968510
51983409
-
AC005943.1
chr19
1578339
1605445
-
AC010132.3
chr7
42909273
42932174
-
AC023055.1
chr12
55757275
55827546
-
AC068946.2
chr2
219209772
219222738
-
AC093525.2
chr16
2496032
2520218
+
AC131160.1
chr3
183815568
183884889
-
AC137834.1
chr12
57249609
57296484
-
ACTN4
chr19
38647649
38731589
+
ADH5
chr4
99070978
99088801
-
AGRN
chr1
1020120
1056118
+
AL133352.1
chr10
100505628
100529881
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-455-5p
chr9
114209449
114209470
+
hsa-miR-361-3p
chrX
85903641
85903663
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC022819.1
chr15
99157231
99161140
-
AC115284.1
chr3
51961212
51974031
-
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.