Entry Detail


General Information

Database ID:exR0723271
RNA Name:WDR1
RNA Type:mRNA
Chromosome:chr4
Starnd:-
Coordinate:
Start Site(bp):10074339End Site(bp):10116949
External Links:ENSG00000071127



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC002985.1
chr19
18907013
18934397
-
AC004832.3
chr22
30409255
30428990
+
AC004922.1
chr7
99325879
99394653
+
AC010422.3
chr19
12643831
12648397
-
AC139530.2
chr17
81703371
81720539
+
ACTG1
chr17
81509971
81523847
-
ADGRB2
chr1
31727117
31764893
-
ADSL
chr22
40346500
40390463
+
AFF4
chr5
132875395
132963634
-
AL022238.4
chr22
40346529
40410054
+
ALDH2
chr12
111766887
111817532
+
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-4700-5p
chr12
120723202
120723223
+
hsa-miR-4700-3p
chr12
120723233
120723258
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC010542.4
chr16
66549280
66551189
+
AC019069.1
chr2
74832655
74833987
-
AD000090.1
chr19
35557956
35581954
+
AL022311.1
chr22
37876148
37895563
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.