Entry Detail


General Information

Database ID:exR0723304
RNA Name:WDR6
RNA Type:mRNA
Chromosome:chr3
Starnd:+
Coordinate:
Start Site(bp):49007062End Site(bp):49015953
External Links:ENSG00000178252



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
A1BG
chr19
58345178
58353492
-
AAGAB
chr15
67200667
67255195
-
ABRA
chr8
106759483
106770244
-
AC004922.1
chr7
99325879
99394653
+
AC008750.8
chr19
51350373
51368099
-
AC124312.1
chr15
24955034
25000276
+
AC245033.1
chr15
82536788
82573194
-
ACLY
chr17
41866917
41930542
-
ACOT8
chr20
45841721
45857405
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
AGAP3
chr7
151085831
151144436
+
AHCY
chr20
34280268
34311802
-
AL136454.1
chr1
192716132
192716653
+
AL139011.2
chr1
160216800
160285130
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-4426
chr1
192716333
192716349
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC012313.3
chr19
58346854
58362751
-
AC016747.4
chr2
61115787
61164825
+
AC067930.1
chr8
143579636
143580670
+
AC245033.4
chr15
82533175
82540008
-
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.