Entry Detail


General Information

Database ID:exR0723415
RNA Name:XPO6
RNA Type:mRNA
Chromosome:chr16
Starnd:-
Coordinate:
Start Site(bp):28097979End Site(bp):28211920
External Links:ENSG00000169180



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABL1
chr9
130713016
130887675
+
AC073082.1
chr2
48632291
48755724
-
AC118553.2
chr1
99970011
100083321
+
ACAP3
chr1
1292390
1309609
-
ACP1
chr2
264140
278283
+
ADAM17
chr2
9488486
9556732
-
ADAMTS19
chr5
129460281
129738683
+
ADGRG2
chrX
18989307
19122637
-
AGBL5
chr2
27042364
27070622
+
AHSA1
chr14
77457870
77469472
+
AKR7A3
chr1
19282573
19288770
-
AL117348.2
chr1
225886696
225924278
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-29a-3p
chr7
130876748
130876769
-
hsa-miR-199a-5p
chr1
172144592
172144614
-
hsa-miR-199b-5p
chr9
128244783
128244805
-
hsa-miR-196b-5p
chr7
27169528
27169549
-
hsa-miR-493-3p
chr14
100869116
100869137
+
hsa-miR-654-5p
chr14
101040234
101040255
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005899.4
chr17
32328441
32329395
+
AC067930.1
chr8
143579636
143580670
+
AL022311.1
chr22
37876148
37895563
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.