Entry Detail


General Information

Database ID:exR0723422
RNA Name:XRCC5
RNA Type:mRNA
Chromosome:chr2
Starnd:+
Coordinate:
Start Site(bp):216107464End Site(bp):216206303
External Links:ENSG00000079246



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AATF
chr17
36948954
37056871
+
AC002985.1
chr19
18907013
18934397
-
AC023055.1
chr12
55757275
55827546
-
AC097637.1
chr3
52221081
52231190
-
AC107871.1
chr15
68184032
68229718
-
AC120057.2
chr17
7240427
7244635
-
AC124312.1
chr15
24955034
25000276
+
AC244197.3
chrX
149477104
149540926
-
AC245033.1
chr15
82536788
82573194
-
ACO1
chr9
32384603
32454769
+
ACSS2
chr20
34872146
34927962
+
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ACTR2
chr2
65227753
65271253
+
ADA
chr20
44619522
44652233
-
ADGRA3
chr4
22345071
22516066
-
ADIPOR2
chr12
1688574
1788674
+
AFF1
chr4
86935002
87141054
+
AHCY
chr20
34280268
34311802
-
AIF1L
chr9
131096476
131123152
+
AIMP1
chr4
106315544
106349456
+
AKIRIN1
chr1
38991276
39006059
+
AKR1A1
chr1
45550543
45570049
+
AL136295.4
chr14
24180395
24190416
-
AL162417.1
chr9
133098121
133163914
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC040162.3
chr16
67882461
67886367
+
AC136475.2
chr11
310139
311141
-
AC245033.4
chr15
82533175
82540008
-
AFDN-DT
chr6
167822103
167826812
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.