Entry Detail



General Information

Database ID:exR0723423
RNA Name:XRCC6
RNA Type:mRNA
Chromosome:chr22
Starnd:+
Coordinate:
Start Site(bp):41621119End Site(bp):41664048
External Links:ENSG00000196419



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AASDHPPT
chr11
106075501
106098699
+
ABR
chr17
1003518
1229738
-
ABRAXAS1
chr4
83459517
83523348
-
AC005020.2
chr7
99558695
99607810
+
AC010132.3
chr7
42909273
42932174
-
AC010422.3
chr19
12643831
12648397
-
AC068946.1
chr2
219075329
219170827
-
AC099811.2
chr17
42119674
42154916
-
AC120057.2
chr17
7240427
7244635
-
ACADVL
chr17
7217125
7225266
+
ACOT8
chr20
45841721
45857405
-
ACTN1
chr14
68874143
68979440
-
ACTR1A
chr10
102461881
102502712
-
ADAM10
chr15
58588809
58749791
-
ADAM15
chr1
155050566
155062775
+
ADCY3
chr2
24819169
24919839
-
AKR1B1
chr7
134442356
134459284
-
AL358113.1
chr9
69035747
69255187
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-17-5p
chr13
91350618
91350640
+
hsa-miR-18a-5p
chr13
91350756
91350778
+
hsa-miR-205-5p
chr1
209432166
209432187
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC079781.5
chr7
97851688
97972985
-
AC093157.1
chr1
101025844
101090513
+
AC144548.1
chr12
110387463
110445548
-
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.