Entry Detail


General Information

Database ID:exR0723433
RNA Name:YBX1
RNA Type:mRNA
Chromosome:chr1
Starnd:+
Coordinate:
Start Site(bp):42682418End Site(bp):42703805
External Links:ENSG00000065978



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABL1
chr9
130713016
130887675
+
ABR
chr17
1003518
1229738
-
AC008764.4
chr19
16577642
16660115
-
AC010422.3
chr19
12643831
12648397
-
AC092143.1
chr16
89919165
89936092
+
AC118553.2
chr1
99970011
100083321
+
AC120057.2
chr17
7240427
7244635
-
AC138811.2
chr16
18788063
18801519
-
ACAD8
chr11
134253495
134265855
+
ACKR3
chr2
236567787
236582354
+
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ADAM11
chr17
44758988
44781846
+
ADD2
chr2
70607618
70768225
-
ADGRL2
chr1
81306160
81992436
+
AEBP2
chr12
19404045
19720801
+
AEN
chr15
88621337
88632281
+
AFG3L2
chr18
12328944
12377227
-
AGL
chr1
99850361
99924023
+
AGO3
chr1
35930718
36072500
+
AGO4
chr1
35808016
35857890
+
AKR1E2
chr10
4786629
4848062
+
AKT1
chr14
104769349
104795751
-
AL136454.1
chr1
192716132
192716653
+
AL928654.3
chr14
105487199
105492267
+
ALDH9A1
chr1
165662216
165698863
-
ALDOA
chr16
30064164
30070457
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC016876.2
chr17
7581964
7584086
-
AC018521.1
chr17
47945424
47981736
+
AC245014.3
chr1
145281116
145281462
+
AL031320.2
chr6
143484979
143507327
+
AL121992.1
chr1
15586136
15603626
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.