Entry Detail


General Information

Database ID:exR0723466
RNA Name:YWHAH
RNA Type:mRNA
Chromosome:chr22
Starnd:+
Coordinate:
Start Site(bp):31944522End Site(bp):31957603
External Links:ENSG00000128245



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AAR2
chr20
36236459
36270918
+
AC005258.1
chr19
2269525
2341172
+
AC010422.3
chr19
12643831
12648397
-
AC091167.2
chr15
90249556
90272208
+
AC104452.1
chr3
49416777
49429314
-
AC138969.1
chr16
16317444
16350590
+
ACTG1
chr17
81509971
81523847
-
ACTR1A
chr10
102461881
102502712
-
AFTPH
chr2
64524305
64593005
+
AKIRIN1
chr1
38991276
39006059
+
AKR1B1
chr7
134442356
134459284
-
AL589666.1
chr6
85557978
85615234
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC079781.5
chr7
97851688
97972985
-
AC132217.1
chr11
2129121
2129964
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.