Entry Detail


General Information

Database ID:exR0723468
RNA Name:YWHAZ
RNA Type:mRNA
Chromosome:chr8
Starnd:-
Coordinate:
Start Site(bp):100916523End Site(bp):100953388
External Links:ENSG00000164924



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AASS
chr7
122073549
122144255
-
ABCB7
chrX
75051048
75156732
-
AC004922.1
chr7
99325879
99394653
+
AC011448.1
chr19
19516227
19536076
+
AC017083.3
chr2
68131238
68261230
-
ACIN1
chr14
23058564
23095614
-
ACSS2
chr20
34872146
34927962
+
ACTB
chr7
5527148
5563784
-
ADCY1
chr7
45574140
45723116
+
ADGRA3
chr4
22345071
22516066
-
ADH5
chr4
99070978
99088801
-
ADPGK
chr15
72751369
72785846
-
AFF1
chr4
86935002
87141054
+
AGMAT
chr1
15571699
15585051
-
AK4
chr1
65147549
65232145
+
AL136454.1
chr1
192716132
192716653
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-4426
chr1
192716333
192716349
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC012615.1
chr19
1874871
1876169
-
AC084082.1
chr8
66112667
66126632
+
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.