Entry Detail


General Information

Database ID:exR0723640
RNA Name:ZMAT2
RNA Type:mRNA
Chromosome:chr5
Starnd:+
Coordinate:
Start Site(bp):140698680End Site(bp):140706686
External Links:ENSG00000146007



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCC1
chr16
15949577
16143074
+
ACSL4
chrX
109624244
109733403
-
ACTA1
chr1
229431245
229434098
-
AD000671.2
chr19
35739252
35745432
-
AEN
chr15
88621337
88632281
+
AGRN
chr1
1020120
1056118
+
AHCY
chr20
34280268
34311802
-
AKR1A1
chr1
45550543
45570049
+
AL928654.3
chr14
105487199
105492267
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-362-3p
chrX
50009005
50009026
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC016747.4
chr2
61115787
61164825
+
AC016876.2
chr17
7581964
7584086
-
AC099524.1
chr16
81738248
81767868
+
AC106881.1
chr4
95549129
95552457
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.