Entry Detail


General Information

Database ID:exR0723644
RNA Name:ZMIZ1
RNA Type:mRNA
Chromosome:chr10
Starnd:+
Coordinate:
Start Site(bp):79068966End Site(bp):79316528
External Links:ENSG00000108175



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC002985.1
chr19
18907013
18934397
-
AC005943.1
chr19
1578339
1605445
-
AC006064.6
chr12
6556886
6607367
-
AC010422.3
chr19
12643831
12648397
-
AC093525.2
chr16
2496032
2520218
+
ACTG1
chr17
81509971
81523847
-
AL121594.1
chr14
35122549
35317474
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-199a-5p
chr1
172144592
172144614
-
hsa-miR-199b-5p
chr9
128244783
128244805
-
hsa-miR-138-5p
chr16
56858527
56858549
+
hsa-miR-185-5p
chr22
20033153
20033174
+
hsa-miR-654-5p
chr14
101040234
101040255
+
hsa-miR-541-3p
chr14
101064548
101064569
+
hsa-miR-1181
chr19
10403505
10403525
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC132217.1
chr11
2129121
2129964
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.