Entry Detail



General Information

Database ID:exR0723872
RNA Name:ZNF512B
RNA Type:mRNA
Chromosome:chr20
Starnd:-
Coordinate:
Start Site(bp):63956704End Site(bp):63969930
External Links:ENSG00000196700



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:Day 42 post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABHD10
chr3
111979010
111993368
+
ADCY6
chr12
48766194
48789037
-
AFDN
chr6
167826922
167972023
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-148a-3p
chr7
25949922
25949943
-
hsa-miR-34a-5p
chr1
9151735
9151756
-
hsa-miR-146a-5p
chr5
160485372
160485393
+
hsa-miR-184
chr15
79209840
79209861
+
hsa-miR-206
chr6
52144401
52144422
+
hsa-miR-34c-5p
chr11
111513451
111513473
+
hsa-miR-378a-3p
chr5
149732867
149732888
+
hsa-miR-148b-3p
chr12
54337278
54337299
+
hsa-miR-449a
chr5
55170586
55170607
-
hsa-miR-146b-5p
chr10
102436520
102436542
+
hsa-miR-625-5p
chr14
65471116
65471136
+
hsa-miR-663a
chr20
26208243
26208264
-
hsa-miR-449b-5p
chr5
55170706
55170727
-
hsa-miR-654-5p
chr14
101040234
101040255
+
hsa-miR-1294
chr5
154347153
154347174
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005562.1
chr17
30576464
30672789
+
AC009133.5
chr16
29808679
29812227
+
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.