Entry Detail



General Information

Database ID:exR0725957
RNA Name:hsa-miR-491-5p
RNA Type:miRNA
Chromosome:chr9
Starnd:+
Coordinate:
Start Site(bp):20716120End Site(bp):20716141
External Links:hsa-miR-491-5p



Disease Information

Disease Name:Vasectomy
Disease Category:Other Diseases
MeSH ID:D014659
Type:Analytical, Diagnostic and Therapeutic Techniques and Equipment Category/Surgical Procedures, Operative
Alias:Vasectomies//Vas Ligation//Ligation, Vas//Ligations, Vas//Vas Ligations//Vas Occlusion//Occlusion, Vas//Occlusions, Vas//Vas Occlusions//Vasectomy Seekers//Seeker, Vasectomy//Seekers, Vasectomy//Vasectomy Seeker//Vasectomy Seekers, Refused//Refused Vasectomy Seeker//Refused Vasectomy Seekers//Seeker, Refused Vasectomy//Seekers, Refused Vasectomy//Vasectomy Seeker, Refused//Intravasal Thread//Intravasal Threads//Thread, Intravasal//Threads, Intravasal//Vas Occlusion, Nonchemical//Nonchemical Vas Occlusion//Nonchemical Vas Occlusions//Occlusion, Nonchemical Vas//Occlusions, Nonchemical Vas//Vas Occlusions, Nonchemical



Expression Detail

GEO ID:GSE43676
Description:microRNA signature is altered in both human epididymis and seminal microvesicles following vasectomy.
Experimental Design:Vasectomy
Case Disease Type:Vasectomized
Case Disease SubType:NA
Case Sample:Vasovasostomized
Control Sample:Normal
Number of Case:1
Number of Control:1
Number of Samples:2





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
IGFBP4
chr17
40443450
40457725
+
SRF
chr6
43171269
43181506
+
CDR2L
chr17
74987632
75005800
+
CENPB
chr20
3783851
3786740
-
RBFOX2
chr22
35738736
36028824
-
SPRED2
chr2
65310851
65432637
-
PHB2
chr12
6965327
6970753
-
PTPRU
chr1
29236516
29326813
+
PTBP3
chr9
112217716
112333667
-
SLC6A6
chr3
14402576
14489349
+
SNAI1
chr20
49982980
49988886
+
NDST1
chr5
150485818
150558211
+
PPP4C
chr16
30075978
30085376
+
LIMD2
chr17
63695888
63701172
-
TTPAL
chr20
44475874
44494603
+
SAMD4B
chr19
39342396
39385710
+
QSOX2
chr9
136206333
136245812
-
C19orf47
chr19
40319536
40348527
-
ZNF574
chr19
42068477
42081552
+
PDXP
chr22
37658723
37666932
+
MEF2D
chr1
156463727
156500779
-
TP53
chr17
7661779
7687550
-
ATXN7L3
chr17
44191805
44200113
-
CPSF7
chr11
61402641
61430031
-
CD151
chr11
832887
839831
+
DIRAS1
chr19
2714567
2721372
-
COL4A2
chr13
110305812
110513209
+
NOTCH2
chr1
119911553
120100779
-
INTS2
chr17
61865367
61928016
-
HDGF
chr1
156742109
156766925
-
miRNA targets:NA
circRNA targets:
circRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa_circ_0000128
chr1
151139409
151139890
+
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC016876.2
chr17
7581964
7584086
-
AC023509.1
chr12
53441741
53467528
+
AC069281.2
chr7
100572232
100578700
-
AL355987.2
chr9
136800366
136829466
+
AL645608.6
chr1
904834
915976
+
H19
chr11
1995176
2001470
-
LINC01278
chrX
63222993
63561095
-
MALAT1
chr11
65497688
65506516
+
NEAT1
chr11
65422774
65445540
+
PCBP2-OT1
chr12
53464468
53465057
+
VPS9D1-AS1
chr16
89711856
89718165
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:23539611
Title:microRNA signature is altered in both human epididymis and seminal microvesicles following vasectomy.
Author:Belleann¨¦e C, L¨¦gar¨¦ C, Calvo E, Thimon V, Sullivan R.
Journal:Hum Reprod. 2013 Jun;28(6):1455-67.
Description:This study may provide new tools for predicting vasovasostomy success and openavenues for the identification of the molecular players involved in male infertility.