exRNAdisease

Entry Detail

---



General Information

Database ID: exR0749624 RNA Name: hsa-miR-27a-3p RNA Type: miRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 13836447 End Site(bp): 13836467 External Links: hsa-miR-27a-3p

Disease Information

Disease Name: Lactation Disease Category: Other Diseases MeSH ID: D007774 Type: Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena Alias: Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations

Expression Detail

GEO ID: GSE75726 Description: Human milk cells and lipids conserve numerous known and novel miRNAs, some of which are differentially expressed during lactation Experimental Design: Time Series Case Disease Type: Lactation Case Disease SubType: NA Case Sample: Post-feeding, month 4 of lactation Control Sample: Post-feeding, month 2 of lactation Number of Case: 5 Number of Control: 5 Number of Samples: 10

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand IGF2BP3 chr7 23310209 23470491 - SOX11 chr2 5692384 5701385 + AEN chr15 88621337 88632281 + SUCO chr1 172532349 172611833 + ALDH3A2 chr17 19648136 19685760 + CD2AP chr6 47477789 47627263 + TTYH3 chr7 2631986 2664802 + C1orf116 chr1 207018522 207032756 - GLTP chr12 109850945 109880541 - PAX9 chr14 36657568 36679362 + TMEM30A chr6 75252924 75284948 - NUAK1 chr12 106063340 106140033 - LGALS8 chr1 236518000 236552981 + ACER3 chr11 76860867 77026797 + NEK2 chr1 211658657 211675630 - CDR2 chr16 22345936 22437165 - B4GALT3 chr1 161171310 161177968 - JRK chr8 142657460 142681968 - KCNK1 chr1 233614106 233672514 + ACLY chr17 41866917 41930542 - TMX4 chr20 7977346 8019805 - PPP1CC chr12 110719680 110742939 - KPNA6 chr1 32108056 32176563 + HTT chr4 3041422 3243960 + NF1 chr17 31094927 31382116 + ETNK1 chr12 22625075 22690665 + ZBTB34 chr9 126860665 126885878 + CANX chr5 179678628 179731641 + PAK1 chr11 77321707 77474635 - GIPC1 chr19 14477760 14496149 - miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0000384 chr12 27867712 27877119 + hsa_circ_0001247 chr22 46125304 46136418 + hsa_circ_0000942 chr19 46020920 46021352 + lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC010980.2 chr2 222317242 222318653 - AC021092.1 chr19 44103007 44113183 - AC022150.4 chr19 52650437 52653284 - AC093010.3 chr3 114314501 114329714 - AL050341.2 chr1 40256427 40257967 - KCNQ1OT1 chr11 2608328 2699994 - LINC01089 chr12 121795267 121803906 - LINC02381 chr12 54126082 54147485 + NEAT1 chr11 65422774 65445540 + SDCBP2-AS1 chr20 1325405 1378735 + SNHG22 chr18 49814023 49851059 + TUG1 chr22 30969245 30979395 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 27074017 Title: Human Milk Cells and Lipids Conserve Numerous Known and Novel miRNAs, Some of Which Are Differentially Expressed during Lactation Author: Alsaweed M, Lai CT, Hartmann PE, Geddes DT, Kakulas F Journal: PLoS One. 2016 Apr 13;11(4):e0152610. Description: We used deep sequencing to profile miRNAs in the cell and lipid fractions of HM obtained post-feeding from 10 lactating women in months 2, 4, and 6 postpartum.