exRNAdisease

Entry Detail

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General Information

Database ID: exR0749631 RNA Name: hsa-miR-296-5p RNA Type: miRNA Chromosome: chr20 Starnd: - Coordinate: Start Site(bp): 58817661 End Site(bp): 58817681 External Links: hsa-miR-296-5p

Disease Information

Disease Name: Lactation Disease Category: Other Diseases MeSH ID: D007774 Type: Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena Alias: Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations

Expression Detail

GEO ID: GSE75726 Description: Human milk cells and lipids conserve numerous known and novel miRNAs, some of which are differentially expressed during lactation Experimental Design: Time Series Case Disease Type: Lactation Case Disease SubType: NA Case Sample: Post-feeding, month 4 of lactation Control Sample: Post-feeding, month 2 of lactation Number of Case: 5 Number of Control: 5 Number of Samples: 10

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACTN4 chr19 38647649 38731589 + CBX1 chr17 48070052 48101478 - EPHB4 chr7 100802565 100827523 - FOXP4 chr6 41546426 41602384 + GOSR2 chr17 46923075 46975524 + RFX1 chr19 13961530 14007039 - WDR5 chr9 134135365 134159968 + ZCCHC3 chr20 297570 300321 + GNL1 chr6 30541377 30557174 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC016876.2 chr17 7581964 7584086 - AL132655.2 chr20 58817132 58817725 - AL355075.4 chr14 20343048 20343685 - AL356488.2 chr1 109100193 109100619 + KCNQ1OT1 chr11 2608328 2699994 - MIR34AHG chr1 9148011 9198906 - MIR663AHG chr20 26167817 26251546 - NEAT1 chr11 65422774 65445540 + NORAD chr20 36045618 36051018 - STAG3L5P-PVRIG2P-PILRB chr7 100336104 100367831 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 27074017 Title: Human Milk Cells and Lipids Conserve Numerous Known and Novel miRNAs, Some of Which Are Differentially Expressed during Lactation Author: Alsaweed M, Lai CT, Hartmann PE, Geddes DT, Kakulas F Journal: PLoS One. 2016 Apr 13;11(4):e0152610. Description: We used deep sequencing to profile miRNAs in the cell and lipid fractions of HM obtained post-feeding from 10 lactating women in months 2, 4, and 6 postpartum.