exRNAdisease

Entry Detail

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General Information

Database ID: exR0749738 RNA Name: hsa-miR-423-5p RNA Type: miRNA Chromosome: chr17 Starnd: + Coordinate: Start Site(bp): 30117095 End Site(bp): 30117117 External Links: hsa-miR-423-5p

Disease Information

Disease Name: Lactation Disease Category: Other Diseases MeSH ID: D007774 Type: Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena Alias: Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations

Expression Detail

GEO ID: GSE75726 Description: Human milk cells and lipids conserve numerous known and novel miRNAs, some of which are differentially expressed during lactation Experimental Design: Time Series Case Disease Type: Lactation Case Disease SubType: NA Case Sample: Post-feeding, month 4 of lactation Control Sample: Post-feeding, month 2 of lactation Number of Case: 5 Number of Control: 5 Number of Samples: 10

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand DCAF7 chr17 63550477 63594279 + PGAM1 chr10 97426191 97433444 + MINK1 chr17 4833340 4898061 + PSME3 chr17 42824385 42843760 + LIMD2 chr17 63695888 63701172 - SYVN1 chr11 65121780 65134533 - KLC2 chr11 66257294 66267860 + MYBL2 chr20 43667019 43716495 + DLGAP4 chr20 36306336 36528637 + CAPN15 chr16 527712 554636 + MAPKBP1 chr15 41774434 41827855 + PAK2 chr3 196739857 196832647 + ACTN4 chr19 38647649 38731589 + C1QTNF6 chr22 37180166 37199385 - MAPK8IP2 chr22 50600793 50613981 + BCORL1 chrX 129981107 130058083 + FAM83H chr8 143723933 143738234 - WDR45B chr17 82614562 82648553 - CDCA7 chr2 173354820 173368997 + PRR12 chr19 49591182 49626439 + CHP1 chr15 41230839 41281887 + TNFAIP3 chr6 137867214 137883312 + IL2RB chr22 37125843 37175054 - RAB8A chr19 16111889 16134234 + HNRNPA2B1 chr7 26173057 26201529 - ATN1 chr12 6924463 6942321 + EIF5AL1 chr10 79512601 79516440 + IGF2BP1 chr17 48997385 49056145 + PPDPF chr20 63520765 63522206 + CTSD chr11 1752755 1764573 - miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0000540 chr14 55799534 55821940 + hsa_circ_0001472 chr5 36953719 36976504 + lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC009133.5 chr16 29808679 29812227 + AC016876.2 chr17 7581964 7584086 - AC021078.1 chr5 149494314 149504670 - AL356488.2 chr1 109100193 109100619 + H19 chr11 1995176 2001470 - KCNQ1OT1 chr11 2608328 2699994 - MIR663AHG chr20 26167817 26251546 - MIRLET7BHG chr22 46053869 46113928 + NEAT1 chr11 65422774 65445540 + STAG3L5P-PVRIG2P-PILRB chr7 100336104 100367831 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 27074017 Title: Human Milk Cells and Lipids Conserve Numerous Known and Novel miRNAs, Some of Which Are Differentially Expressed during Lactation Author: Alsaweed M, Lai CT, Hartmann PE, Geddes DT, Kakulas F Journal: PLoS One. 2016 Apr 13;11(4):e0152610. Description: We used deep sequencing to profile miRNAs in the cell and lipid fractions of HM obtained post-feeding from 10 lactating women in months 2, 4, and 6 postpartum.