exRNAdisease

Entry Detail

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General Information

Database ID: exR0749748 RNA Name: hsa-miR-448 RNA Type: miRNA Chromosome: chrX Starnd: + Coordinate: Start Site(bp): 114823524 End Site(bp): 114823545 External Links: hsa-miR-448

Disease Information

Disease Name: Lactation Disease Category: Other Diseases MeSH ID: D007774 Type: Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena Alias: Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations

Expression Detail

GEO ID: GSE75726 Description: Human milk cells and lipids conserve numerous known and novel miRNAs, some of which are differentially expressed during lactation Experimental Design: Time Series Case Disease Type: Lactation Case Disease SubType: NA Case Sample: Post-feeding, month 4 of lactation Control Sample: Post-feeding, month 2 of lactation Number of Case: 5 Number of Control: 5 Number of Samples: 10

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ANKRD52 chr12 56237807 56258384 - EPHA4 chr2 221418027 221574202 - HTD2 chr3 58306262 58318574 + MSTO1 chr1 155610188 155614971 + QSER1 chr11 32892820 32993316 + RDH11 chr14 67676800 67695793 - RNF169 chr11 74748849 74842413 + RPP14 chr3 58306247 58324695 + SH3PXD2A chr10 103594027 103855543 - SIX4 chr14 60709539 60724351 - SNAI2 chr8 48917598 48921740 - TTLL7 chr1 83865024 83999150 - WASF2 chr1 27404230 27490167 - ZBTB34 chr9 126860665 126885878 + miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0001454 chr4 154524454 154533552 + lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand NEAT1 chr11 65422774 65445540 + OIP5-AS1 chr15 41283990 41309737 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 27074017 Title: Human Milk Cells and Lipids Conserve Numerous Known and Novel miRNAs, Some of Which Are Differentially Expressed during Lactation Author: Alsaweed M, Lai CT, Hartmann PE, Geddes DT, Kakulas F Journal: PLoS One. 2016 Apr 13;11(4):e0152610. Description: We used deep sequencing to profile miRNAs in the cell and lipid fractions of HM obtained post-feeding from 10 lactating women in months 2, 4, and 6 postpartum.