exRNAdisease

Entry Detail

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General Information

Database ID: exR0749749 RNA Name: hsa-miR-4485-3p RNA Type: miRNA Chromosome: chr11 Starnd: - Coordinate: Start Site(bp): 10508277 End Site(bp): 10508296 External Links: hsa-miR-4485-3p

Disease Information

Disease Name: Lactation Disease Category: Other Diseases MeSH ID: D007774 Type: Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena Alias: Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations

Expression Detail

GEO ID: GSE75726 Description: Human milk cells and lipids conserve numerous known and novel miRNAs, some of which are differentially expressed during lactation Experimental Design: Time Series Case Disease Type: Lactation Case Disease SubType: NA Case Sample: Post-feeding, month 4 of lactation Control Sample: Post-feeding, month 2 of lactation Number of Case: 5 Number of Control: 5 Number of Samples: 10

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand C11orf24 chr11 68261338 68272001 - CDK4 chr12 57747727 57756013 - CKAP5 chr11 46743048 46846308 - CYB561A3 chr11 61348745 61362299 - SERINC1 chr6 122443351 122471807 - NES chr1 156668763 156677407 - NDUFB11 chrX 47142216 47145504 - FUBP1 chr1 77944055 77979110 - RPL27 chr17 42998273 43002959 + YEATS2 chr3 183697797 183812624 + CIRBP chr19 1259384 1274880 + DNM1 chr9 128191655 128255248 + MAP3K11 chr11 65597756 65615382 - RPL13 chr16 89560657 89566828 + EXOSC6 chr16 70246778 70251940 - SBF2 chr11 9778667 10294207 - HSPA8 chr11 123057489 123063230 - RPS27A chr2 55231903 55235853 + EIF3F chr11 7970251 8001862 + RNASEH2C chr11 65714005 65720818 - FAU chr11 65120630 65122177 - HSP90AB1 chr6 44246166 44253888 + RPS3 chr11 75399515 75422280 + NR3C1 chr5 143277931 143435512 - SPG11 chr15 44562696 44663678 - MTRNR2L6 chr7 142666272 142667718 + LGR4 chr11 27365961 27472790 - FRMD8 chr11 65386621 65413525 + CRTC3 chr15 90529923 90645345 + MTRNR2L12 chr3 96617188 96618236 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand MALAT1 chr11 65497688 65506516 + XIST chrX 73820649 73852723 - AD000090.1 chr19 35557956 35581954 + LINC01002 chr19 198264 246544 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 27074017 Title: Human Milk Cells and Lipids Conserve Numerous Known and Novel miRNAs, Some of Which Are Differentially Expressed during Lactation Author: Alsaweed M, Lai CT, Hartmann PE, Geddes DT, Kakulas F Journal: PLoS One. 2016 Apr 13;11(4):e0152610. Description: We used deep sequencing to profile miRNAs in the cell and lipid fractions of HM obtained post-feeding from 10 lactating women in months 2, 4, and 6 postpartum.