exRNAdisease

Entry Detail

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General Information

Database ID: exR0749798 RNA Name: hsa-miR-519a-3p RNA Type: miRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 53762397 End Site(bp): 53762418 External Links: hsa-miR-519a-3p

Disease Information

Disease Name: Lactation Disease Category: Other Diseases MeSH ID: D007774 Type: Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena Alias: Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations

Expression Detail

GEO ID: GSE75726 Description: Human milk cells and lipids conserve numerous known and novel miRNAs, some of which are differentially expressed during lactation Experimental Design: Time Series Case Disease Type: Lactation Case Disease SubType: NA Case Sample: Post-feeding, month 4 of lactation Control Sample: Post-feeding, month 2 of lactation Number of Case: 5 Number of Control: 5 Number of Samples: 10

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ARL4A chr7 12686856 12690958 + CAMK2N1 chr1 20482391 20486210 - CCDC93 chr2 117915478 118014133 - CCSAP chr1 229321011 229343294 - CDK6 chr7 92604921 92836594 - CIT chr12 119685791 119877320 - CLCN6 chr1 11806096 11848079 + EEA1 chr12 92770637 92929331 - EIF5A2 chr3 170888418 170908644 - FAM13A chr4 88725955 89111398 - FYCO1 chr3 45917899 45995824 - LDLRAD3 chr11 35943981 36232136 + LONP2 chr16 48244300 48363122 + MAGI3 chr1 113390515 113685923 + MBP chr18 76978827 77133683 - NAA16 chr13 41311267 41377030 + OCRL chrX 129539849 129592561 + PDRG1 chr20 31944337 31952046 - PLAGL2 chr20 32192504 32207743 - RGMA chr15 93035273 93089204 - SEC16A chr9 136440096 136483759 - SLC16A14 chr2 230034982 230068993 - SLC46A3 chr13 28700064 28718970 - SLC7A2 chr8 17497088 17570573 + SMAD7 chr18 48919853 48952052 - SYAP1 chrX 16719612 16765340 + TAOK3 chr12 118149801 118372907 - ZFAND4 chr10 45615500 45672780 - miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0001495 chr5 68470703 68471364 + hsa_circ_0000494 chr13 76134888 76143643 + hsa_circ_0000018 chr1 15860731 15863309 + lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002094.1 chr17 28357647 28381697 + AC010542.4 chr16 66549280 66551189 + AC015871.3 chr15 79920195 79922455 - AC021078.1 chr5 149494314 149504670 - AC021092.1 chr19 44103007 44113183 - AC024940.6 chr12 31280422 31280895 - AC087477.2 chr15 96354237 96405235 + AC243964.3 chr19 44631573 44725217 - AL137782.1 chr13 75549773 75807120 + AL158206.1 chr9 19453209 19455173 + CKMT2-AS1 chr5 81201341 81301565 - EPB41L4A-AS1 chr5 112160526 112164818 + ERICD chr8 140636281 140638283 + H19 chr11 1995176 2001470 - HAGLR chr2 176164051 176188958 - HOTAIR chr12 53962308 53974956 - MAGI2-AS3 chr7 79452877 79471208 + MIR17HG chr13 91347820 91354579 + NEAT1 chr11 65422774 65445540 + STAG3L5P-PVRIG2P-PILRB chr7 100336104 100367831 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 27074017 Title: Human Milk Cells and Lipids Conserve Numerous Known and Novel miRNAs, Some of Which Are Differentially Expressed during Lactation Author: Alsaweed M, Lai CT, Hartmann PE, Geddes DT, Kakulas F Journal: PLoS One. 2016 Apr 13;11(4):e0152610. Description: We used deep sequencing to profile miRNAs in the cell and lipid fractions of HM obtained post-feeding from 10 lactating women in months 2, 4, and 6 postpartum.