exRNAdisease

Entry Detail

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General Information

Database ID: exR0749890 RNA Name: hsa-miR-744-5p RNA Type: miRNA Chromosome: chr17 Starnd: + Coordinate: Start Site(bp): 12081909 End Site(bp): 12081930 External Links: hsa-miR-744-5p

Disease Information

Disease Name: Lactation Disease Category: Other Diseases MeSH ID: D007774 Type: Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena Alias: Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations

Expression Detail

GEO ID: GSE75726 Description: Human milk cells and lipids conserve numerous known and novel miRNAs, some of which are differentially expressed during lactation Experimental Design: Time Series Case Disease Type: Lactation Case Disease SubType: NA Case Sample: Post-feeding, month 4 of lactation Control Sample: Post-feeding, month 2 of lactation Number of Case: 5 Number of Control: 5 Number of Samples: 10

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AP5S1 chr20 3820524 3828838 + ARHGDIA chr17 81867721 81871378 - ARL8A chr1 202133404 202144743 - C8orf82 chr8 144525733 144529132 - CLSTN1 chr1 9728926 9823984 - CMIP chr16 81445170 81711762 + DLGAP4 chr20 36306336 36528637 + DNAJC30 chr7 73680918 73683453 - EEF1A2 chr20 63488014 63499185 - FAM219A chr9 34398184 34458570 - FAM83H chr8 143723933 143738234 - MGRN1 chr16 4616493 4690974 + MIDN chr19 1248553 1259140 + NFIX chr19 12995608 13098796 + NRARP chr9 137299631 137302271 - PHB2 chr12 6965327 6970753 - PRKCD chr3 53156009 53192717 + PRR12 chr19 49591182 49626439 + RAI14 chr5 34656328 34832612 + SCN1B chr19 35030470 35040449 + SH3GL1 chr19 4360370 4400547 - SMAD3 chr15 67063763 67195169 + SPRED2 chr2 65310851 65432637 - SYVN1 chr11 65121780 65134533 - WNT5A chr3 55465715 55490539 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002116.1 chr19 36008638 36014235 - AC008738.7 chr19 33207129 33207639 + AL356488.2 chr1 109100193 109100619 + GAS5 chr1 173858559 173868882 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 27074017 Title: Human Milk Cells and Lipids Conserve Numerous Known and Novel miRNAs, Some of Which Are Differentially Expressed during Lactation Author: Alsaweed M, Lai CT, Hartmann PE, Geddes DT, Kakulas F Journal: PLoS One. 2016 Apr 13;11(4):e0152610. Description: We used deep sequencing to profile miRNAs in the cell and lipid fractions of HM obtained post-feeding from 10 lactating women in months 2, 4, and 6 postpartum.