exRNAdisease

Entry Detail

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General Information

Database ID: exR0749899 RNA Name: hsa-miR-877-5p RNA Type: miRNA Chromosome: chr6 Starnd: + Coordinate: Start Site(bp): 30584332 End Site(bp): 30584351 External Links: hsa-miR-877-5p

Disease Information

Disease Name: Lactation Disease Category: Other Diseases MeSH ID: D007774 Type: Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena Alias: Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations

Expression Detail

GEO ID: GSE75726 Description: Human milk cells and lipids conserve numerous known and novel miRNAs, some of which are differentially expressed during lactation Experimental Design: Time Series Case Disease Type: Lactation Case Disease SubType: NA Case Sample: Post-feeding, month 4 of lactation Control Sample: Post-feeding, month 2 of lactation Number of Case: 5 Number of Control: 5 Number of Samples: 10

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABR chr17 1003518 1229738 - DNAJB6 chr7 157335381 157417439 + EIF2AK1 chr7 6022247 6059175 - FOSL1 chr11 65892049 65900573 - IGF2BP1 chr17 48997385 49056145 + MAPK8IP2 chr22 50600793 50613981 + PHTF2 chr7 77798792 77957503 + PLD3 chr19 40348456 40380439 + SMG1 chr16 18804853 18926454 - TRAF7 chr16 2155698 2178129 + USP54 chr10 73497538 73625953 - ANAPC7 chr12 110372900 110403730 - EIF4ENIF1 chr22 31436977 31496108 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC010442.1 chr5 466124 473098 - AC092718.4 chr16 81030770 81031485 + DNAAF4-CCPG1 chr15 55355248 55498360 - DSCAM-AS1 chr21 40383083 40385358 + LINC00910 chr17 43338741 43389199 - LINC01278 chrX 63222993 63561095 - NEAT1 chr11 65422774 65445540 + SNHG16 chr17 76557764 76565348 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 27074017 Title: Human Milk Cells and Lipids Conserve Numerous Known and Novel miRNAs, Some of Which Are Differentially Expressed during Lactation Author: Alsaweed M, Lai CT, Hartmann PE, Geddes DT, Kakulas F Journal: PLoS One. 2016 Apr 13;11(4):e0152610. Description: We used deep sequencing to profile miRNAs in the cell and lipid fractions of HM obtained post-feeding from 10 lactating women in months 2, 4, and 6 postpartum.