exRNAdisease

Entry Detail

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General Information

Database ID: exR0750160 RNA Name: hsa-miR-339-5p RNA Type: miRNA Chromosome: chr7 Starnd: - Coordinate: Start Site(bp): 1022990 End Site(bp): 1023012 External Links: hsa-miR-339-5p

Disease Information

Disease Name: Lactation Disease Category: Other Diseases MeSH ID: D007774 Type: Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena Alias: Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations

Expression Detail

GEO ID: GSE75726 Description: Human milk cells and lipids conserve numerous known and novel miRNAs, some of which are differentially expressed during lactation Experimental Design: Time Series Case Disease Type: Lactation Case Disease SubType: NA Case Sample: Post-feeding, month 6 of lactation Control Sample: Post-feeding, month 2 of lactation Number of Case: 5 Number of Control: 5 Number of Samples: 10

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABL2 chr1 179099330 179229684 - ARHGDIA chr17 81867721 81871378 - ATXN7 chr3 63864557 64003462 + EDEM1 chr3 5187646 5219958 + FEM1A chr19 4791734 4801273 + FOXP1 chr3 70952817 71583993 - G3BP2 chr4 75642782 75724525 - MMD chr17 55392622 55421924 - NCOA6 chr20 34689097 34825651 - NUSAP1 chr15 41320794 41381050 + PRDM15 chr21 41798225 41879482 - PTPA chr9 129110950 129148946 + SLC44A1 chr9 105244622 105439171 + STAT3 chr17 42313324 42388568 - VCP chr9 35056064 35072627 - WDR4 chr21 42843094 42879568 - ZNF689 chr16 30602558 30624012 - miRNA targets: NA circRNA targets: circRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa_circ_0000120 chr1 117944807 118009049 + lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004069.1 chr4 105137280 105140619 - AC145207.5 chr17 81878425 81881106 - GAS5 chr1 173858559 173868882 - H19 chr11 1995176 2001470 - KCNQ1OT1 chr11 2608328 2699994 - LINC01578 chr15 92819540 92899701 + NEAT1 chr11 65422774 65445540 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 27074017 Title: Human Milk Cells and Lipids Conserve Numerous Known and Novel miRNAs, Some of Which Are Differentially Expressed during Lactation Author: Alsaweed M, Lai CT, Hartmann PE, Geddes DT, Kakulas F Journal: PLoS One. 2016 Apr 13;11(4):e0152610. Description: We used deep sequencing to profile miRNAs in the cell and lipid fractions of HM obtained post-feeding from 10 lactating women in months 2, 4, and 6 postpartum.