exRNAdisease

Entry Detail

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General Information

Database ID: exR0750173 RNA Name: hsa-miR-3609 RNA Type: miRNA Chromosome: chr7 Starnd: + Coordinate: Start Site(bp): 98881700 End Site(bp): 98881723 External Links: hsa-miR-3609

Disease Information

Disease Name: Lactation Disease Category: Other Diseases MeSH ID: D007774 Type: Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena Alias: Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations

Expression Detail

GEO ID: GSE75726 Description: Human milk cells and lipids conserve numerous known and novel miRNAs, some of which are differentially expressed during lactation Experimental Design: Time Series Case Disease Type: Lactation Case Disease SubType: NA Case Sample: Post-feeding, month 6 of lactation Control Sample: Post-feeding, month 2 of lactation Number of Case: 5 Number of Control: 5 Number of Samples: 10

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand IGF2 chr11 2129112 2141238 - MAP3K7 chr6 90513573 90587072 - MYH9 chr22 36281277 36388067 - PIK3C2A chr11 17077730 17207983 - CCNY chr10 35247025 35572669 + CCT2 chr12 69585426 69601570 + GPRIN3 chr4 89236383 89307800 - ING5 chr2 241687085 241729478 + NUP98 chr11 3671083 3797792 - P2RX5-TAX1BP3 chr17 3663063 3696194 - PBX2 chr6 32184733 32190202 - RPLP0 chr12 120196699 120201235 - TAX1BP3 chr17 3662895 3668679 - WDR74 chr11 62832342 62841809 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL356488.2 chr1 109100193 109100619 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 27074017 Title: Human Milk Cells and Lipids Conserve Numerous Known and Novel miRNAs, Some of Which Are Differentially Expressed during Lactation Author: Alsaweed M, Lai CT, Hartmann PE, Geddes DT, Kakulas F Journal: PLoS One. 2016 Apr 13;11(4):e0152610. Description: We used deep sequencing to profile miRNAs in the cell and lipid fractions of HM obtained post-feeding from 10 lactating women in months 2, 4, and 6 postpartum.