exRNAdisease

Entry Detail

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General Information

Database ID: exR0753435 RNA Name: AC002310.1 RNA Type: lncRNA Chromosome: chr16 Starnd: + Coordinate: Start Site(bp): 30534752 End Site(bp): 30537149 External Links: ENSG00000235560

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CEBPB chr20 50190830 50192668 + CHTF18 chr16 788046 800737 + CREBBP chr16 3725054 3880713 - CXXC4 chr4 104468308 104494901 - FRAT2 chr10 97332497 97334729 - FZD8 chr10 35638249 35642278 - HDAC3 chr5 141620876 141636849 - KCNK1 chr1 233614106 233672514 + LRWD1 chr7 102464956 102473168 + MSH5 chr6 31739677 31762676 + MSH5-SAPCD1 chr6 31740020 31764851 + MTPN chr7 135926760 135977359 - OTUD5 chrX 48922028 48958386 - PABPN1 chr14 23321289 23326185 + PECR chr2 215996329 216082955 - PEX5 chr12 7188685 7218574 + POU3F2 chr6 98834574 98839458 + PSENEN chr19 35745600 35747519 + RNF126 chr19 647526 663233 - SAMD10 chr20 63974116 63980008 - SIX1 chr14 60643421 60658259 - SLC38A1 chr12 46183063 46270017 - USP24 chr1 55066359 55215364 - VCP chr9 35056064 35072627 - miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.