exRNAdisease

Entry Detail

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General Information

Database ID: exR0753456 RNA Name: AC004812.2 RNA Type: lncRNA Chromosome: chr12 Starnd: + Coordinate: Start Site(bp): 120116907 End Site(bp): 120119000 External Links: ENSG00000277283

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACADM chr1 75724347 75787575 + CALM1 chr14 90396502 90408268 + DDX42 chr17 63773603 63819317 + EIF4G2 chr11 10797050 10808940 - EXOC5 chr14 57200507 57268905 - FBXO21 chr12 117141988 117190531 - GTF2H3 chr12 123633739 123662604 + MT-ND2 chrMT 4470 5511 + NDUFB11 chrX 47142216 47145504 - NUP62 chr19 49906825 49929763 - PRR36 chr19 7868719 7874390 - RPP21 chr6 30345131 30346884 + SNU13 chr22 41673933 41690504 - TRIM39-RPP21 chr6 30328907 30346854 + UBE2J1 chr6 89326625 89352722 - miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.