exRNAdisease

Entry Detail

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General Information

Database ID: exR0753502 RNA Name: AC006504.5 RNA Type: lncRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 27793431 End Site(bp): 27984984 External Links: ENSG00000267575

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CCNA2 chr4 121816444 121823933 - DVL3 chr3 184155377 184173614 + FKBP10 chr17 41812680 41823213 + FTL chr19 48965309 48966879 + ING1 chr13 110712736 110723339 + MT-ND4 chrMT 10760 12137 + MYO9B chr19 17075781 17214537 + NEK8 chr17 28725897 28743455 + NR2F6 chr19 17231883 17245940 - OTUB1 chr11 63985853 64001811 + PIEZO1 chr16 88715338 88785220 - PNKP chr19 49859882 49878351 - POFUT1 chr20 32207880 32238658 + SFPQ chr1 35176378 35193145 - SLC4A2 chr7 151057210 151076526 + SPCS3 chr4 176319966 176332245 + STMN1 chr1 25884181 25906991 - SUMO3 chr21 44805617 44818779 - TBC1D1 chr4 37891084 38139175 + TCF3 chr19 1609290 1652615 - TMEM8B chr9 35814451 35865518 + UBQLN1 chr9 83659968 83707958 - XYLT2 chr17 50346126 50363138 + ZNF765 chr19 53389793 53430413 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC006504.7 chr19 27802838 27803472 + HCP5 chr6 31463170 31478936 + NIFK-AS1 chr2 121649320 121728563 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.